A colorimetric and fluorescent probe for sulfite/bisulfite based on conjugated benzothiazole derivative and imaging application in living cells
作者：Li Zhang, Lei Wang, Xuan Zhang,* Zhi-Jia Zhu
關鍵字：Colorimetric and fluorescent probe, Sulfite/bisulfite, Benzothiazole derivative, Intramolecular charge transfer, Fluorescence imaging
論文來源：期刊
具體來源：Journal of Photochemistry & Photobiology A: Chemistry 395 (2020) 112498
發表時間：2020年
A new colorimetric and fluorescent probe 2 for SO32?/HSO3? detection was developed based on a conjugated benzothiazole derivative. The probe 2 was red color in aqueous solution and became colorless in the presence of SO32?/HSO3?, accompanied by a fluorescence quenching. It was rationalized by an intramolecular charge transfer (ICT) mechanism, where the addition of SO32?/HSO3? to the vinyl double bond broken the conjugation and blocked the ICT process. This probe showed highly selective detection of SO32?/HSO3? compared with other sulfur-containing species and featured a detection limit of 2.01 μM. Moreover, the present probe was also successfully used for the fluorescence imaging of intracellular sulfur dioxide derivatives in living HeLa cells.