AngewChem--Construction of Protein Nanowires through Cucurbit[8]uril-based Highly Specific HostGuest Interactions: An Approach to the Assembly of Functional Proteins
作者：Hou, Chunxi; Li, Jiaxi; Zhao, Linlu; et al.
關鍵字：Cucurbit[8]uril, Host-guest systems, Nanowires, Proteins, Self-assembly
論文來源：期刊
發表時間：2013年
Getting your proteins in a row: Self-assembled protein nanowires were designed by utilizing highly specific supramolecular interactions of cucurbit[8]uril (CB[8]) and a tripeptide FGG-tag attached on the N-termini of dimeric glutathione S-transferase (GST). With the aid of enzyme simulation, model protein GST was converted into a selenoenzyme glutathione peroxidase mimic, and the CB[8]-induced Se-FGG-GST(Y6C) nanowires demonstrated excellent antioxidative capacity.